From The Guardian: “UK regulators have given the go-ahead for the first clinical trial of the use of the psychedelic drug dimethyltriptamine (DMT) to treat depression. The trial will initially give the drug – known as the “spirit molecule” for the powerful hallucinogenic trips it induces – to healthy individuals, but it is expected to be followed by a second trial in patients with depression, where DMT will be given alongside psychotherapy…”
Read MoreFrom www.guardian.com: “Kerry Rhodes says a series of hallucinogenic trips he took as part of a documentary helped him understand himself more deeply. “Once it kicks in there are prisms and shapes and stuff like that, I could see visually stunning stuff. I literally had to tell myself, ‘You’re OK, you’re good, this is what you signed up for.’” The first “purge” – vomit – into a bucket brought a particularly bizarre vision: Rhodes, at his playing peak one of the NFL’s pre-eminent safeties, was brought face to face with a foetus…”
Read More“Oakland, California has become the second city in the United States to decriminalize the use and possession of psychedelic mushrooms, The Associated Press reports. The Oakland City Council unanimously approved a resolution Tuesday night, just weeks after Denver voters narrowly approved a similar measure. Along with mushrooms containing psilocybin, the resolution also decriminalizes other psychedelics naturally derived from plants or fungi, such as ayahuasca, peyote and DMT. Synthetic psychedelics like LSD and MDMA, are still illegal…”
Read More“Mini-brains" grown in the lab have proven to be useful models of the real thing, giving researchers an accurate neuroscience platform without testing on animals. Now, a team of scientists from Brazil have doped the mini-brains with a form of the psychedelic drug DMT, to study the effects on neural pathways….”
Read MoreBy Dr. Andrew Gallimore for www.grahamhancock.com: “Terence McKenna’s mushroom-inspired vision of an ancient, almost god-like, super-intelligence is both awe-inspiring and terrifying. However, whilst there is no reason to assume that such an unimaginably powerful alien intelligence couldn’t exist somewhere within this Universe or, perhaps, in some hidden dimensions beyond it, few fear having to confront such a creature: these frightening dimensions can be safely tucked away amongst the more exotic branches of modern mathematical physics and their occupants relegated to the pages of pulp sci-fi novels. At least that’s the case until one encounters DMT…”
Read MoreFrom Forbes.com: “This isn’t the psychedelic you remember from college. It isn’t an eight-hour marathon experience tripping through the woods like Alice. It’s fast-acting, short-duration — sometimes lasting as briefly as seven minutes — and is a rocket-ship ride into the center of the cosmos. In a recent European study, after one single use, the substance 5-MeO-DMT was shown to produce sustained enhancement of satisfaction with life, and easing of anxiety, depression and post-traumatic stress disorder (PTSD)…”
Read MoreFrom Metro.co.uk: “I’m drowning in mud, my brain has turned into noodles, and I’ve just tipped a bucket of my own vomit over my head. This is the reality of doing ayahuasca, a transformative hallucinogen. Despite a terrifying trip involving ghosts, broccoli, and frogs, I’m so glad I did it. I’ve finally found inner peace and my life has radically changed. But let’s rewind a bit…”
Read More“I recently had a chance to have a conversation with a woman who is leading the scientific pathway to researching the mysterious compound DMT… Dr. Jimo Borjigin from the University of Michigan. Dr. Borjigin received her PhD from John’s Hopkins University and has published ground-breaking research regarding increased brain oscillatory speeds & coherence following cardiac arrest, the neurochemical fluctuations following asphyxia-based cardiac arrest, the discovery of DMT production in the pineal gland of live rats, and now the most recent study that has observed comparable levels of DMT to common neurotransmitters (dopamine, serotonin, and norepinephrine) in the brain…”
Read More““DMT is not just in plants, but also can be detected in mammals,” says Jimo Borjigin, Ph.D., of the Department of Molecular and Integrative Physiology. Her interest in DMT came about accidentally. Before studying the psychedelic, her research focused on melatonin production in the pineal gland…”
Read More“New research published in Scientific Reports indicates that the rat brain is capable of synthesizing and releasing a powerful psychedelic drug called dimethyltryptamine (DMT). Scientists suspect that the same could be true in humans…”
Read More“DMT is being closely examined by researchers in many fields from around the world, but acclaimed psychologist Dr. Ede Frecska, Chairman of Psychiatry at the University of Debrecen in Hungary, is pushing the envelope, aiming to demonstrate that DMT can extend the life of consciousness beyond clinical death for a longer duration of time than is currently possible…”
Read More“This probably isn’t a shock to anyone following trends in tech and startups, particularly the glorification of the 8-trillion hour workweek (#hustle). But business owners, entrepreneurs, and technologists are also turning to other hallucinogens to awaken higher levels of consciousness in hopes of influencing favorable business results…”
Read More“Ross and Dwyer are at the centre of the country's first clinical trial of psychedelic drugs for treating severe depression in the terminally ill. Within a month, they will begin recruiting 40 depressed and incurable patients in an attempt to relieve their distress with a novel treatment: between one and two 25-milligram doses of synthetic psilocybin, the psychedelic ingredient found in "magic mushrooms", accompanied by intensive psychotherapy sessions…”
Read More“A new study published in Scientific Reports definitively observed that indolethylamine-N-methyltransferase (INMT) is found in both human and rat brains throughout the cerebral cortex, choroid plexus, and pineal gland. The importance of this finding is based on the fact that INMT is the enzyme responsible for biosynthesizing DMT from tryptamine. Prior studies were inconclusive regarding this based on out-dated protocols that lacked sensitivity…”
Read More“A new systematic review states that serotonergic hallucinogens help users recognize emotions in facial expressions. Sufferers of anxiety and depression often only read negative emotions in other people's faces, adding to their malaise. While more research is needed, psychedelics could prove to be a powerful agent in battling mental health disorders…”
Read More“A total of five religious groups now are allowed to use the hallucinogenic in their ceremonies. Thanks to Health Canada, some folks in Quebec and Ontario are one step closer to finding god, as three more exemptions have been granted to religious groups to allow them to import ayahuasca, a powerful and controversial hallucinogenic, according to a report by Global News.”…
Read MoreMike Tyson said, after smoking 5meO-DMT (of the Bufo Alvarius toad), “Once I smoked it, everything went boom! When I came down my brain was functioning and I could talk but I was saying ‘I f***ed up’. I killed myself because I killed my ego and my life totally changed…”
Read More“The first formal centre for psychedelic research in the world will launch at Imperial College London today. Funded by more than £3 million from five founding donors, the new Imperial Centre for Psychedelic Research will build on over a decade of pioneering work in this area carried out at Imperial, including a clinical trial that has kick-started global efforts to develop psilocybin therapy into a licensed treatment for depression…”
Read More“People who experiment with microdosing claim that it can help a person to think more creatively, feel less anxious, and sharpen focus. But despite plenty of anecdotal evidence and Silicon Valley’s ample claims that these positive effects are real, scientists still can’t definitively say that microdosing actually works. Bringing us closer to a clear answer is a new study showing that microdosing can indeed have beneficial effects — but not without potential downsides…”
Read More“A new study – “Neurochemical models of near-death experiences: A large-scale study based on the semantic similarity of written reports” – has set out to quantify the possible links by comparing a bunch of NDE accounts (625) with a huge number of ‘trip reports’ (more than 15,000) “spanning experiences with 165 psychoactive substances of ten different pharmacological classes”…”
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