Posts tagged Research
Lab-Grown Mini-Brains Dosed with DMT to Study Psychedelic Effects

“Mini-brains" grown in the lab have proven to be useful models of the real thing, giving researchers an accurate neuroscience platform without testing on animals. Now, a team of scientists from Brazil have doped the mini-brains with a form of the psychedelic drug DMT, to study the effects on neural pathways….”

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The Most Psychedelic Technology in Human History is Here, and it’s Called Neuralink

“One could say that all software impacts our consciousness in some way, from grandma’s dopamine-fueled enjoyment of a casino game to the banal ubiquity of spreadsheet programs at shitty office jobs everywhere, to the way that weaponized Facebook ads affected elections in 30 countries. But thanks to Elon Musk and other pioneers in brain-computer or brain-machine interfaces (known as BMI), software, in conjunction with brain-implanted hardware, will soon have the power to impact our psyche directly, at the level of our neurons…”

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(New!) Interview with Leading DMT Researcher Dr. Jimo Borjigin

“I recently had a chance to have a conversation with a woman who is leading the scientific pathway to researching the mysterious compound DMT… Dr. Jimo Borjigin from the University of Michigan. Dr. Borjigin received her PhD from John’s Hopkins University and has published ground-breaking research regarding increased brain oscillatory speeds & coherence following cardiac arrest, the neurochemical fluctuations following asphyxia-based cardiac arrest, the discovery of DMT production in the pineal gland of live rats, and now the most recent study that has observed comparable levels of DMT to common neurotransmitters (dopamine, serotonin, and norepinephrine) in the brain…”

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Psychedelic Compound DMT Officially Discovered in Human Brain

““DMT is not just in plants, but also can be detected in mammals,” says Jimo Borjigin, Ph.D., of the Department of Molecular and Integrative Physiology. Her interest in DMT came about accidentally. Before studying the psychedelic, her research focused on melatonin production in the pineal gland…”

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DMT Research To Ask If Spirit Molecule Can Extend Life Beyond Clinical Death

“DMT is being closely examined by researchers in many fields from around the world, but acclaimed psychologist Dr. Ede Frecska, Chairman of Psychiatry at the University of Debrecen in Hungary, is pushing the envelope, aiming to demonstrate that DMT can extend the life of consciousness beyond clinical death for a longer duration of time than is currently possible…”

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New DMT Study Provides Additional Link to Gamma Wave Formation

“A new study published in Scientific Reports definitively observed that indolethylamine-N-methyltransferase (INMT) is found in both human and rat brains throughout the cerebral cortex, choroid plexus, and pineal gland. The importance of this finding is based on the fact that INMT is the enzyme responsible for biosynthesizing DMT from tryptamine. Prior studies were inconclusive regarding this based on out-dated protocols that lacked sensitivity…”

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Scientists Rethink Psychedelics As Attitudes Change Toward Formerly Illicit Drugs

“The irony. The generation who brought psychedelic drugs to the attention of the world, may just be the ones who use them as medicine to treat anxiety and depression or simply to face death. But while researchers around the world are looking at some formerly illicit drugs in a new way, they’re doing it with caution...”

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Smoking Psychedelic Toad Milk Could Alleviate Depression For Up To Four Weeks

“A milky, psychoactive secretion that oozes from the glands of a North American toad could provide a fast-acting and extremely potent treatment for depression, according to a new study. The amphibian in question is the Colorado river toad, or Bufo alvarius…”

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Imperial College London Launches World’s First Centre for Psychedelics Research

“The first formal centre for psychedelic research in the world will launch at Imperial College London today. Funded by more than £3 million from five founding donors, the new Imperial Centre for Psychedelic Research will build on over a decade of pioneering work in this area carried out at Imperial, including a clinical trial that has kick-started global efforts to develop psilocybin therapy into a licensed treatment for depression…”

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Scientists Microdosed Rats With DMT, and It Was Both Good and "Concerning"

“People who experiment with microdosing claim that it can help a person to think more creatively, feel less anxious, and sharpen focus. But despite plenty of anecdotal evidence and Silicon Valley’s ample claims that these positive effects are real, scientists still can’t definitively say that microdosing actually works. Bringing us closer to a clear answer is a new study showing that microdosing can indeed have beneficial effects — but not without potential downsides…”

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Psychedelic Afterlife: Researchers Determine Which Hallucinogenic ‘Trip’ is Most Similar to the Near-Death Experience

“A new study – “Neurochemical models of near-death experiences: A large-scale study based on the semantic similarity of written reports” – has set out to quantify the possible links by comparing a bunch of NDE accounts (625) with a huge number of ‘trip reports’ (more than 15,000) “spanning experiences with 165 psychoactive substances of ten different pharmacological classes”…”

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Toad Medicine: New Psychedelic Knowledge under Construction?

“The increasing supply and consumption of the so-called “toad medicine” in various parts of the world has led to a series of claims without theoretical, or historical support, and have allowed it to become an important lucrative activity for various stakeholders…”

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